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Pathophysiology/Disorders of Hematopoietic System-Part 1

by Scott
Across
Yellow discoloration of skin
Hereditary disorder, RBC loses spherical shape, cannot traverse the spleen.
Blood fluid, about 90% water by weight, 8% proteins, with globulins
Typical syndrome name that causes increase in flow resistance, sickle cell, polycythemia.
In sickle cell, no glutamic acid, substituted by this amino acid.
Test employed for immune hemolytic anemia; antiglobulin test.
Name of antibodies that come from foreign source, transfusion reactions and hemolytic disease of newborn.
Bleeding spots in skin, tiny, indicative of other diseases
Term used for reduction in platelet number.
Type of mutation, inherited, named after Dutch city.
Erythroblastosis ____________; HDN also.
RBCs derived from precursor cells; bone marrow.
Water soluble form is known as this type of bilirubin
Serious hyperbilirubinemia in neonate, jaundice and possible brain damage.
In newborn, enlarged spleen and liver, decreased albumin, massive edema. _______ fetalis
Down
Destructive anemias can increase the secretion of this renal hormone.
These plaques disturb blood flow, endothelial damage
Anemia caused by vitamin B9 deficiency; __________ acid.
May cause thrombocytosis; _____________ vera.
Inherited disorder of hemoglobin synthesis. Name.
Seen in disturbed hemoglobin synthesis; excess alpha chains form precipitates; ___________ bodies.
Number of human blood groups.
Types of anemia that results in enlarged RBCs; impaired DNA synthesis.
Resulting anemia from deficiency in intrinsic factor.
Substance causes platelet adhesion, carrier protein for coagulation factor V111.
Unable to bind oxygen; opposite oxyhemoglobin
Another term for Mediterranean anemia
RBC count measures total number of RBCs in this quantity of blood.
Widespread coagulation and bleeding in vascular compartment; abbreviation.
Added to blood, prevents clotting by chelating ionic calcium.
Polycythemia vera is also called this type of polycythemia.