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PDAC

Across
Type of neutropenia resulting in fever
When mutated, these stromal cells produce fibrin. They’re real “star”s!
5-FU
In shorthand, this pyrimidine-based chemotherapy agent is the “precious stone” of PDAC treatment
10. This three-drug combination has conflicting results in PDAC
These enzymes convert irinotecan to SN-38
These cells line pancreatic ducts (PDAC starts here)
Elevated levels of this, found in bile, would have excluded you from the NAPOLI-1 trial.
One in a billion
Down
Common 1st line mPDAC regimen for Patients w/ good PS
Type of tumor found in hormone producing cells of the pancreas
PDAC precursor
Factor that determines treatment choice
Often the first symptom of tumors in head of pancreas
More holes (stuff gets in) and less drainage (but it can’t get out)
Leucovorin AKA
This process makes the liposome larger in size. Also happens to some Pirates. Ahrr!
Cytotoxic agents associated with neuropathy
Nanoparticle albumin