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Chapter 13 – Innate Immunity

Across
___ make up less than 1% of the WBC count. They release histamines and proteolytic enzymes. They are believed to play a role in allergies and parasitic infections.
There are ___ phases of the complement system.
The ____ 1. system which is found in blood and consists of 20 different proteins, is crucial to the activity of antibodies. It allows the body to localize infection and destroy invading organisms.
The innate immune system is comprised of two lines of defense. The epithelial layer and the ____ response
___ coat negatively-charged particles on cell membranes, which then enhances the recognition and binding of phagocytic cells to invading microorganisms.
____ which when hydrated form mucus, bind to pathogens to trap them and wash away potential invaders.
These cells have large granulocytes and only make up 1-4% of the WBC count. These cells do not ingest cellular debris and they play a role in parasitic infections and allergies.
___ come into contact with cell surfaces or send signals that trigger a host’s proinflammatory and antimicrobial responses.
Down
___ are one of the more efficient phagocytic cells and essential to the clearance of bacteria and debris. They also act as a major initiator of the adaptive immune response.
These phagocytic cells with neutral staining granulocytes, make up 55% of the WBC count and are capable of amoeboid-like movement. They are early responders in innate immunity, but lay dormant in the blood and bone marrow until needed.
stimulate the migration of leukocytes to an area of inflammation
__ cells spontaneously kill target organisms and assist in T-cell polarization.
___ are the largest of all WBC. They mature into macrophages and participate in the inflammatory response, as well as phagocytizing cellular debris and foreign substances.
___ cells act as a bridge between the innate and adaptive immune response systems. They function as key antigen-presenting cells.
___ or pathogen-associated molecular patterns refer to the conserved structure of invading pathogens that allows them to be recognized by the innate immune system.