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Mechanisms of Cell Injury

Across
This type of virus which stimulates host cell replication and may produce cancer/tumours
Is a condition when the blood supply to the body tissue is good but the blood doesn't have enough oxygen in it
A pattern of cell death where the DNA condenses into a solid, shrunken, basophilic membrane
In this, signs of irreversible injury can be seen within 30-40mins after ischemia
Free radicals are highly reactive particles and this is a free radical injury
A pattern of cell death where there is fragmentation of the pyknotic nucleus
A lack of oxygen to the body cells results in what?
Is seen when there is extensive damage to plasma membranes, swelling of lysosomes and a massive calcium influx into the cells
Cell death becomes replaced with large masses composed of what?
What is taken up avidly by the mitochondria after reoxygenation and permanently poisons the cell?
This type of necrosis involves liquefying of structures
Is due to a decrease of cellular metabolism caused by explosive viral replication
Is seen in gangrenous necrosis if more liquefaction occurs
Down
Is a type of coagulative necrosis that is seen in tuberculosis infections. It is cheesy and white in appearance
Is the architecture of cells that are visible using a powerful electron microscope
An inadequate blood supply to an organ or part of the body
Enzymatic digestion where catalytic enzymes come from lysosomes of cell death is called what?
A lack of oxygen
These cause auto-oxidation of fatty acids within the membrane phospholipids
Is a result from ATP generation slowing/stopping and NA/K pumps not working properly.
This type of necrosis is when denaturation of proteins happens first and the shape of the cell is maintained
May be an indicator of reversible cell injury, only occurs in cells involved in fat metabolism and is a form of intracellular accumulation
Is a type of necrosis where there are areas of fat destruction due to a release of activated pancreatic enzymes. The fat cells liquefy and lipases split the triglyceride esters contained in the fat cells